Aims

PlatesThe aim of the European Prosthetic Joint Infection Cohort (EPJIC) Study is to improve the management of Prosthetic Joint Infection (PJI) and develop consensus guidelines across Europe. By systematic analysis of consecutively included patients with PJI, factors associated with best outcome regarding infection (assessed by the infection-free interval) and joint function (assessed by the degree of pain, mobility, range of motion) will be determined in a longitudinal prospective study with long-term follow-up.

In the European Prosthetic Joint Infection Cohort Study evaluable patient groups will be generated enabling the comparison between different surgical and antimicrobial treatment concepts. This study aim is achieved by:

  • Recruitment of patients with PJI of joint prostheses (e.g. hip, knee, shoulder and ankle joints) in participating study centers.
  • Systematic collection of clinical, radiological, harmacological, laboratory, microbiological, treatment and outcome data using a standardized electronic CRF (eCRF).
  • Ensuring long-term follow-up of patient with evaluation regarding infection, functional result and health-related quality of life.

Second aim of EPJIC is to provide a broad infrastructure for the implementation of sub-projects in the frame of PJI (clinical and laboratory studies) with specific research questions. Both researchers who are already participating in the Cohort and external academic and private companies are welcome to submit their proposals as described in our submission procedure.